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Full NameDr Nollaig Bourke

School of Medicine

Trinity College Dublin

Webpage:www.tcd.ie

Email Address:Email hidden; Javascript is required.

Research Fields
  • genetics, genomics and molecular biology
  • infectious disease and the immune system
  • physiology and non-communicable disease
  • cancer/oncology
Postgrad Medical Specialties
  • Medicine
  • Pathology
Medical Subspecialties
  • Geriatric Medicine
  • Infectious diseases
  • Immunology
  • Physiology
  • Vascular Medicine
My Work

My research aims to determine novel biomarkers of health and disease in ageing, as well as elucidating cellular mechanisms that drive the enhanced systemic inflammation that often occurs with ageing (“inflammageing”). My research focuses on investigating the specific innate immune signalling pathways, particularly type I interferon and inflammasome signalling, that result in pathological inflammation and decreased immunity in older adults. I collaborate with many clinical and scientific colleagues and my lab is now exploring the dysregulation of these mechanisms across specific disease states associated with accelerated ageing and/or pathological inflammation e.g. HIV, ANCA-associated vasculitis, type II diabetes, cancer.