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Full NameProfessor John Reynolds

School of Medicine

Trinity College Dublin

Webpage:medicine.tcd.ie

Email Address:Email hidden; Javascript is required.

Research Fields

cancer/oncology

Postgrad Medical Specialties

Medicine
Surgery

Medical Subspecialties

Immunology
Oncology

My Work

Themes:
1. Studies on visceral obesity and liver and the relationship to cancer in humans. Platforms included immunology, and inflammation/metabolism.
2. Studies on inflammation to cancer pathways, in particular Barrett's oesophagus to oesophageal adenocarcinoma, and inflammatory bowel disease to colorectal adenocarcinoma.
3. Studies on prediciton of response and resistance to chemotherapy and radiation therapy in gastrointestinal cancer.
4. Leading International Clinical Trial: Neo-AEGIS, comparing preoperative chemotherapy and chemoradiation prior to resection of oesophageal adenocarcinoma. Translational studies focusing on gene arrays, miRNA, and PET imaging as predictors of response.
5. The impact of major surgery on immune cells and the inflammatory response (oesophageal and lung cancer).
6. Studies (neuroendocrine, functional MRI) of gut-brain interaction underlying weight loss and anorexia after major cancer surgery.