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Full NameProfessor Roman Romero-Ortuno

Discipline of Medical Gerontology, School of Medicine

Trinity College Dublin

Email Address:Email hidden; Javascript is required.

Research Fields
  • physiology and non-communicable disease
  • neuroscience and mental health
  • bioengineering/medical devices
  • epidemiology/population health research
  • Other
Other Research Fields:

Ageing Physiology, Geriatric Medicine, Frailty

Postgrad Medical Specialties
  • Medicine
  • General Practice
  • Public Health
  • Sports and Exercise Medicine
Medical Subspecialties
  • Cardiology
  • Community Medicine
  • Dementia
  • Geriatric Medicine
  • Health Informatics
  • Neurology
  • Neurophysiology
  • Neuropsychiatry
  • Pharmacology
  • Physiology
  • Vascular Medicine
My Work

The key direction of my research is towards a better understanding and modelling of the physiology of ageing across systems with particular attention to the concept of frailty in older adults. Frailty is characterised by dysregulation in multiple physiological systems and vulnerability to stressors, with risk of adverse outcomes including premature disability and mortality.

With population ageing worldwide, the early detection of frailty is crucial because some of its drivers can be intervened upon. My research has contributed new tools for the operationalisation of the clinical concept of frailty in ways that add value to practice and research.

My current research programme into early detection of frailty in older adults (FRAILMatics) has been awarded €1.5 million in funding as part of the Science Foundation Ireland President of Ireland Future Research Leaders Award programme (2019-2024). FRAILMatics is analysing very large datasets of measurements of mild physiological stresses across physiological systems in participants from The Irish Longitudinal Study on Ageing and a clinical cohort in St James’s Hospital.
FRAILMatics will pave the way towards the development of medical devices that can help clinicians identify frailty at an early stage.

Read more about FRAILMatics on: and

My publications are on: