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Prof Frank Kee

Department:Centre for Public Health

Division:Institute of Health Sciences

Organisation:Queen's University Belfast

Webpage:http://www.qub.ac.uk/research-centres/CentreforPublicHealth/

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Research Fields
  • epidemiology/population health research
Postgrad Medical Specialites
  • Medicine
  • Public Health
Medical Subspecialties
  • Clinical Trials
  • Community Medicine
  • Other
Other Medical Specialties:

Stratified Medicine

My Work

Our group works both in traditional (and genetic) epidemiology and in clinical and public health trials. In the epidemiology field we have partnered with many European and global consortia and have access to large cohort datasets with biomarker measurements (eg through the MORGAM Project https://www.thl.fi/morgam/ and the BiomarCaRE consortium www.biomarcare.eu/)
We undertake complex public health trials in a wide range of areas. These trials may be focussed on individual behaviours such as physical activity or diet or may take a whole population approach (eg mass communication, choice architecture or environmental change).
We have expertise in early phase studies in the design and development of new interventions, and their testing in feasibility and pilot studies. As well as conducting Phase III and Phase IV trials (including health economic assessments), we have skills in implementation science, health services research and knowledge translation.
We work across multiple sectors partnering with clinicians, public health bodies, primary care and policy makers to maximise translational opportunities.

Potential Projects

A number of possible projects include :
1. A study of how clinicians? perceptions and attitudes to therapeutic risk-benefit trade-offs compare with those of their patients and what the implications might be for stratified medicine. This study would use the methodology of discrete choice experiments.

2. A study of the relationship between plasma biomarkers and lifestyle habits, particularly physical activity, and their joint association with prediction of cardiovascular outcomes in population based European cohorts. This study would have access to cohorts of >300,000 subjects.

3. What are the associations between behavioural economic traits (like risk and time preference) and genetic and epigenetic markers measured in the Northern Ireland Study for the Longitudinal Study of Aging (NICOLA)?