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Full NameProfessor Frank Barry
Medicine
National University of Ireland Galway
Webpage:remedi.ie
Email Address:Email hidden; Javascript is required.
- cell and developmental biology/regenerative medicine
- Medicine
- Surgery
- Sports and Exercise Medicine
- Orthopaedic surgery
- Rheumatology
- Vascular Medicine
Rapid progress over the last two decades in the isolation and biological characterization of stem cells has placed them at the forefront of current efforts in regenerative medicine. Stem cells represent an important element in regenerative strategies for tissue repair by virtue of their availability in large numbers, relative ease of preparation and capacity to differentiate into specific tissue types. Pluripotent embryonic stem cells (ESC) have extraordinary potential in terms of tissue repair involving all germ lines. Induced pluripotent stem cells (iPSCs) generated by reprogramming of human somatic cells have a similar, although not identical, phenotype to ESCs.
Our work is concerned with (1) assessing the therapeutic utility of stromal cell or stem cell transplantation in selected diseases, mainly musculoskeletal conditions, (2) using iPSC as cellular models of disease and (3) understanding the phenotype, regulation and control of human and animal stem cells.