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Full NameProfessor Owen P. Smith

Paediatric and Adolescent Medicine

University College Dublin

Webpage:nationalchildrensresearchcentre.ie

Email Address:Email hidden; Javascript is required.

Research Fields
  • genetics, genomics and molecular biology
  • cancer/oncology
  • clinical trials
Postgrad Medical Specialties
  • Paediatrics
Medical Subspecialties
  • Adolescent medicine
  • Haematology
  • Oncology
My Work

One of the main areas of my clinical research has been in evidence-based randomised peer-reviewed paediatric haemato-oncology clinical trials, focusing on clinical questions within all domains of child and adolescent blood and cancer. I am an active member / principal investigator (UK and European Study Groups) involved in international peer-review trial design.
One of my main areas of translational research for the past two decades has been elucidating the relationship between the protein C (PC) activation pathway and the systemic inflammatory response sepsis syndromes. To date, this research has made significant clinical and basic scientific contributions to the emergence of a new paradigm regarding the patho-biology of severe sepsis / septic shock.