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Full NameDr Damian Downey
Centre for Experimental Medicine
Queen's University Belfast
Webpage:qub.ac.uk
Email Address:Email hidden; Javascript is required.
- genetics, genomics and molecular biology
- infectious disease and the immune system
- physiology and non-communicable disease
- epidemiology/population health research
- clinical trials
- Medicine
- Paediatrics
- Pathology
- Adolescent medicine
- Gastroenterology
- Health Informatics
- Infectious diseases
- Immunology
- Pharmacology
- Physiology
- Respiratory Medicine
My main clinical research interest is cystic fibrosis (CF). I work with a range of colleagues that includes, clinicians, allied health professionals, a clinical research team and basic scientists to create a translational research program in CF. My focus is to optimise clinical response to established and new therapies. My investigator led projects currently involve;
-Multi-modal analysis of pulmonary exacerbations in CF, exploring the potential for clinical and inflammatory biomarkers to predict response to treatment
-The bacterial impact of non-antimicrobial therapies in CF and repurposing drugs
-The impact of co-morbidities in CF by deep patient phenotyping and utilising pre-clinical models to assess the mechanisms involved
-Exploration of Patient Reported Outcome Measures for clinical trials
-Treatment plans for respiratory tract fungal disease in CF
-Exploration of cellular signals in response to CFTR modulation
I also have additional research programs in bronchiectasis and pneumonia. My projects currently involve, pathogen identification in community acquired pneumonia and assessing outcome measures in bronchiectasis
These projects form a network of basic science and clinical projects.