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Full NameProfessor Peter Kelly
- neuroscience and mental health
- clinical trials
- Other
Clinical trials, cerebrovascular disease, cardiovascular disease
- Medicine
- Pathology
- Neurology
- Vascular Medicine
Background;
The WHO estimates that stroke is the second leading cause of global death, leading cause of acquired disability, and a major contributor to dementia and healthcare costs.
Aim:
The Stroke Clinical Trials Network Ireland comprises 8 'core' Irish hospitals affiliated with all 6 Irish universities, Hospital Groups, and Clinical Research Centres (CRCs). Governance, management, training, communications, and fundraising capacity to improve the efficiency of conducting high-quality clinical trials of stroke prevention, acute treatment, and recovery are being established, thus increasing access of Irish patients to new treatments. The SCTNI conducts investigator led and industry led randomised clinical trials to prevent and treat stroke.
Ongoing stroke trials are being partnered with the Network. We have developed an international Definitive Intervention trial, to investigate low-dose colchicine versus placebo plus usual care to prevent recurrent vascular events after minor non-cardioembolic ischaemic stroke, called CONVINCE. A development portfolio of additional trials along pilot/feasibility, application for new funding, and definitive intervention phases is under way.