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Full NameProfessor Denis Shields
Medicine
University College Dublin
Webpage:shieldslab.ucd.ie
Email Address:Email hidden; Javascript is required.
- genetics, genomics and molecular biology
- clinical trials
- Medicine
- Cardiology
- Dermatology
- Gastroenterology
- Haematology
- Health Informatics
- Hospice and palliative medicine
- Infectious diseases
- Immunology
- Neonatology
- Nephrology
- Pharmacology
- Rheumatology
- Vascular Medicine
Bioinformatics is used in our group to characterise and discover patterns of associations of sequence related data to disease processes. We have interests in genetic sequence variation in disease, in collaboration with rheumatologists and cardiologists. We have been developing specialised software to make sense of protein and peptide data, with a particular interest in the role of protein breakdown into peptides and the roles of digestive and inflammatory proteases in gastrointestinal disorders. We are also interested in the development of beneficial nutritional products for medical needs, using software methods to predict design and analyse the compositions of peptides and other protein factors in the foods. Computing tools used include machine learning, with varied applications, sequence analysis, statistical modelling and visualisation.
A listing of publications is available at:
https://scholar.google.com/citations?hl=en&user=KxEwP9UAAAAJ&view_op=list_works&sortby=pubdate