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Full NameProfessor Alistair Nichol

Dept of Critical Care Medicine

University College Dublin

Webpage:iccctn.org

Email Address:Email hidden; Javascript is required.

Research Fields

epidemiology/population health research
clinical trials

Postgrad Medical Specialties

Medicine
Anaesthetics
Emergency Medicine
Public Health

My Work

The Irish Critical Care Trials Group was established by a group of clinician researchers back in 2007.

In 2010 we commenced out first interventional randomised controlled trial of a statin in 534 patients with Acute Respiratory Distress Syndrome (NEJM, October 2014, see CTG publications).

Since then the ICC-CTG, completed a demographic study of the burden of critical care in Ireland in 2014, to determine feasibility for future interventional studies (in preparation) and established a point prevalence program (see research).

The ICC-CTG members have taken part in six international interventional randomised controlled trials coordinated by the Australian and New Zealand Intensive Care Research Centre, Melbourne, Australia. These were published in the NEJM in 2014 (ARISE), 2017 (TRANSFUSE) and 2019 (SPICE), Lancet in 2015 (EPO-TBI), American Journal of Respiratory and Critical Care Medicine in 2019 (PHARLAP), JAMA in 2020 (PEPTIC) see publications.

Furthermore, the CTG is currently engaged in a number of large randomized controlled trials (see current research) in collaboration with Canada, Australia and New Zealand and the United Kingdom.

These efforts to date demonstrate that key support is a team of highly motivated ICU clinicians who are committed to the IC- CTG and who work in all the major ICUs in Ireland and who in combination provide care to the overwhelming majority of critically ill patients in the Island of Ireland.