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Supervisor Database

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Full NameDr Susan Byrne

FutureNeuro and Dept of Paediatrics and Child Health

Royal College of Surgeons in Ireland

Webpage:rcsi.com

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Research Fields
  • genetics, genomics and molecular biology
  • cell and developmental biology/regenerative medicine
  • neuroscience and mental health
  • epidemiology/population health research
Postgrad Medical Specialties
  • Medicine
  • Paediatrics
Medical Subspecialties
  • Adolescent medicine
  • Child and Adolescent Psychiatry
  • Health Informatics
  • Neurology
My Work

Dr Susan Byrne is a Senior Lecturer in FutureNeuro/department of paediatrics and child health in RCSI, and consultant paediatric neurologist in CHI at Crumlin. Susan graduated from medical school in Trinity College in 2005. Between 2009 and 2012 she completed her PhD in genetic epidemiology where she learned about the value of patient registries in furthering our understanding of disease and working towards a cure. Prior to her move back to Ireland in 2021, Susan worked as a Paediatric Neurology consultant in the Evelina London Children’s hospital. During her time there, she specialized in neuroinflammatory disorders of childhood and paediatric stroke, as well as general paediatric neurology including neurogenetic conditions. During the Covid-19 pandemic Susan was involved in describing the neurological features of PIMS-TS. Susan works as part of the CORAL study (The Impact of CORona Virus Pandemic on InfAnts Born During Lockdown) and leads the neurodevelopmental arm. The CORAL team were the first to report deficits in communication in infants born during the COVID-19 pandemic. Since completing her PhD, Susan’s main area of interest is in genotype/phenotype correlation in the neurogenetic disorders of childhood and the capabilities of neurogenetic diagnostic testing. Together with her collaborators in CHI and FutureNeuro, she has established the CINDI registry for children with neurogenetic conditions, and the EpiFUN study which seeks to further genetic diagnostic rates in children with neurogenetic disorders.

Potential Projects

My research focuses on the mechanisms underlying child development in both typically developing children and in those with a neurogenetic condition. There are two different types of projects on offer.

Neurogenetics/CINDI/EpiFUN: The PhD project could focus on the epidemiology of children with undiagnosed neurogenetic disorders using the CINDI register, bioinformatic techniques to improve diagnostic rates in children with neurogenetic disorders, and the additional use of transcriptome/methylation pattern analysis in making a genetic diagnosis.

Child development/CORAL: The PhD project would focus on the neurodevelopmental outcomes in children born during the pandemic compared to a post pandemic cohort of babies.

Emerging Supervisor

Bioinformatics: Prof Gianpiero Cavalleri, Dr Katie Benson

Child development/CORAL: Prof Jonathan Hourihane

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