Supervisor Database Search
Guidance for ICAT Supervisors
The ICAT Supervisor list is reviewed annually by the partner universities and updated online in March/April each year.
You can read about the ICAT supervisor selection process and eligibility criteria below:
Terms of reference/guide to supervising ICAT Fellows.
You can read the terms of reference for supervisors actively supervising ICAT Fellows below:
Supervisor Database
Search for supervisors below. You can filter your search using the options and select multiple fields by holding CTRL (Cmd on Mac) + clicking multiple options in a list.
Full NameDr Rebecca Coll
School of Medicine, Dentistry and Biomedical Sciences
Queen's University Belfast
Webpage:qub.ac.uk
Email hidden; Javascript is required.
- genetics, genomics and molecular biology
- infectious disease and the immune system
- cell and developmental biology/regenerative medicine
- physiology and non-communicable disease
- Medicine
- Surgery
- Anaesthetics
- General Practice
- Obstetrics and Gynaecology
- Paediatrics
- Pathology
- Oral and Maxillofacial Medicine
- Cardiology
- Clinical Trials
- Dementia
- Dermatology
- Endocrinology
- Gastroenterology
- Geriatric Medicine
- Haematology
- Infectious diseases
- Immunology
- Nephrology
- Neurology
- Orthopaedic surgery
- Pharmacology
- Physiology
- Respiratory Medicine
- Rheumatology
Our research seeks to understand the molecular mechanisms of inflammation, and how inflammasomes function in human health and disease. A particular focus has been small-molecule inhibitors of the NLRP3 inflammasome including landmark studies on the NLRP3 inhibitor MCC950 (Coll et al., Nature Medicine, 2015; Coll et al. Nature Chemical Biology, 2019). By using emerging technologies such as human induced pluripotent stem cell-derived myeloid cells combined with CRISPR-Cas9 gene editing, the lab is characterizing the function and regulation of human inflammasomes. This includes studies on the role of the primate-lineage protein families known as CARD-only proteins (COPs) in inflammasome signaling, and novel temperature regulated mechanisms that regulate NLRP3 and the innate immune system. We are passionate about characterizing inflammasome biology in human systems which will ultimately accelerate the development of new treatments for patients with inflammatory diseases.
I am open to a wide range of specialties that are interested in studying the innate immune response in their disease of interest.
Prof Danny McAuley
Prof Cecelia O'Kane
Professor Charuhas Thakar
Dr Helen Groves
Dr Pamela Jane McDowell
Dr Ashley Elliot